Abstract
Background
Methods
Results
Conclusion
Keywords
Introduction
- Harnett N.G.
- van Rooij S.J.H.
- Ely T.D.
- Lebois L.A.M.
- Murty V.P.
- Jovanovic T.
- et al.
- Harnett N.G.
- Stevens J.S.
- Fani N.
- van Rooij S.J.H.
- Ely T.D.
- Michopoulos V.
- et al.
Methods and Materials
Participants

Measures
MRI Procedures
- Harnett N.G.
- van Rooij S.J.H.
- Ely T.D.
- Lebois L.A.M.
- Murty V.P.
- Jovanovic T.
- et al.
Statistical Analyses
Results
Participant demographics and psychological characteristics



Reactivity to fearful and neutral faces and ST
Seed-based rsFC and ST

Discussion
- Harnett N.G.
- van Rooij S.J.H.
- Ely T.D.
- Lebois L.A.M.
- Murty V.P.
- Jovanovic T.
- et al.
- Harnett N.G.
- Stevens J.S.
- Fani N.
- van Rooij S.J.H.
- Ely T.D.
- Michopoulos V.
- et al.
- Rowland G.E.
- Mekawi Y.
- Michopoulos V.
- Powers A.
- Fani N.
- Bradley B.
- et al.
Uncited reference
Weathers FW, Blake DD, Schnurr PP, Kaloupek DG, Marx BP, Keane TM (2013): Life Events Checklist for DSM-5 (LEC-5) - PTSD: National Center for PTSD [General Information]. Retrieved June 21, 2021, from https://www.ptsd.va.gov/professional/assessment/te-measures/life_events_checklist.asp
Weathers FW, Litz BT, Keane TM, Palmieri PA, Marx BP, Schnurr PP (2013): PTSD Checklist for DSM-5 (PCL-5) - PTSD: National Center for PTSD [General Information]. Retrieved June 21, 2021, from www.ptsd.va.gov
Dalenberg C, Carlson E (2010): Severity of Dissociative Symptoms - Adult (Brief Dissociative Experiences Scale (DES-B) – Modified). American Psychiatric Association: Online Assessment Measures. Retrieved September 29, 2021, from https://www.psychiatry.org/psychiatrists/practice/dsm/educational-resources/assessment-measures
Acknowledgements
Supplementary Material
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Article info
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Disclosures: Dr. Lebois reports unpaid membership on the Scientific Committee for the International Society for the Study of Trauma and Dissociation (ISSTD), grant support from the National Institute of Mental Health (NIMH), K01 MH118467, and the Julia Kasparian Fund for Neuroscience Research. Dr. Lebois also reports spousal IP payments from Vanderbilt University for technology licensed to Acadia Pharmaceuticals unrelated to the present work. Dr. Neylan has received research support from NIH, VA, and Rainwater Charitable Foundation, and consulting income from Jazz Pharmaceuticals. In the last three years Dr Clifford has received research funding from the NSF, NIH and LifeBell AI, and unrestricted donations from AliveCor Inc, Amazon Research, the Center for Discovery, the Gates Foundation, Google, the Gordon and Betty Moore Foundation, MathWorks, Microsoft Research, Nextsense Inc, One Mind Foundation, the Rett Research Foundation, and Samsung Research. Dr Clifford has financial interest in AliveCor Inc and Nextsense Inc. He also is the CTO of MindChild Medical and CSO of LifeBell AI and has ownership in both companies. These relationships are unconnected to the current work. Dr. Rauch reports grants from NIH during the conduct of the study; personal fees from SOBP (Society of Biological Psychiatry) paid role as secretary, other from Oxford University Press royalties, other from APP (American Psychiatric Publishing Inc.) royalties, other from VA (Veterans Administration) per diem for oversight committee, and other from Community Psychiatry/Mindpath Health paid board service, including equity outside the submitted work; other from National Association of Behavioral Healthcare for paid Board service; and Leadership roles on Board or Council for SOBP, ADAA (Anxiety and Depression Association of America), and NNDC (National Network of Depression Centers). SS has received funding from the Florida Medical Malpractice Joint Underwriter’s Association Dr. Alvin E. Smith Safety of Healthcare Services Grant; Allergan Foundation; the NIH/NIA-funded Jacksonville Aging Studies Center (JAX-ASCENT; R33AG05654); and the Substance Abuse and Mental Health Services Administration (1H79TI083101-01); and the Florida Blue Foundation. Dr. Jones has no competing interests related to this work, though he has been an investigator on studies funded by AstraZeneca, Vapotherm, Abbott, and Ophirex. Dr. Joormann receives consulting payments from Janssen Pharmaceuticals. Over the past 3 years, Dr. Pizzagalli has received consulting fees from Albright Stonebridge Group, Boehringer Ingelheim, Compass Pathways, Concert Pharmaceuticals, Engrail Therapeutics, Neumora Therapeutics (former BlackThorn Therapeutics), Neurocrine Biosciences, Neuroscience Software, Otsuka Pharmaceuticals, Sunovion Pharmaceuticals, and Takeda Pharmaceuticals; honoraria from the Psychonomic Society and the American Psychological Association (for editorial work) and Alkermes, and research funding from NIMH, Dana Foundation, Brain and Behavior Research Foundation, and Millennium Pharmaceuticals. In addition, he has received stock options from Neumora Therapeutics (former BlackThorn Therapeutics), Compass Pathways, Engrail Therapeutics, and Neuroscience Software. Dr. Harte has no competing interests related to this work, though in the last three years he has received research funding from Aptinyx and Arbor Medical Innovations, and consulting payments from Aptinyx, Heron Therapeutics, and Eli Lilly. Dr. Elliott reports support from the National Institutes of Health (NIH) through Grant Numbers R01HD079076 & R03HD094577: Eunice Kennedy Shriver National Institute of Child Health & Human Development; National Center for Medical Rehabilitation Research. He also reports funding from New South Wales Health, Spinal Cord Injury Award (2020-2025) and consulting fees (< $15,000 per annum) from Orofacial Therapeutics, LLC. In the past 3 years, Dr. Kessler was a consultant for Cambridge Health Alliance, Canandaigua VA Medical Center, Holmusk, Partners Healthcare, Inc., RallyPoint Networks, Inc., and Sage Therapeutics. He has stock options in Cerebral Inc., Mirah, PYM, and Roga Sciences. Dr. Koenen’s research has been supported by the Robert Wood Johnson Foundation, the Kaiser Family Foundation, the Harvard Center on the Developing Child, Stanley Center for Psychiatric Research at the Broad Institute of MIT and Harvard, the National Institutes of Health, One Mind, the Anonymous Foundation, and Cohen Veterans Bioscience. She has been a paid consultant for Baker Hostetler, Discovery Vitality, and the Department of Justice. She has been a paid external reviewer for the Chan Zuckerberg Foundation, the University of Cape Town, and Capita Ireland. She has had paid speaking engagements in the last three years with the American Psychological Association, European Central Bank. Sigmund Freud University – Milan, Cambridge Health Alliance, and Coverys. She receives royalties from Guilford Press and Oxford University Press. Dr. McLean served as a consultant for Walter Reed and for Arbor Medical Innovations. Dr. Ressler has performed scientific consultation for Bioxcel, Bionomics, Acer, Takeda, and Jazz Pharma; serves on Scientific Advisory Boards for Sage and the Brain Research Foundation, and he has received sponsored research support from Takeda, Brainsway and Alto Neuroscience. Dr. Harnett reports grant support from the National Institute of Mental Health, K00 MH119603. All other authors report no biomedical financial interests or potential conflicts of interest.
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